KEGG   Bos taurus (cow): 281105
Entry
281105            CDS       T01008                                 
Symbol
CTSB
Name
(RefSeq) cathepsin B precursor
  KO
K01363  cathepsin B [EC:3.4.22.1]
Organism
bta  Bos taurus (cow)
Pathway
bta04140  Autophagy - animal
bta04142  Lysosome
bta04210  Apoptosis
bta04612  Antigen processing and presentation
bta04621  NOD-like receptor signaling pathway
bta04924  Renin secretion
Brite
KEGG Orthology (KO) [BR:bta00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    281105 (CTSB)
   04140 Autophagy - animal
    281105 (CTSB)
  09143 Cell growth and death
   04210 Apoptosis
    281105 (CTSB)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    281105 (CTSB)
   04612 Antigen processing and presentation
    281105 (CTSB)
  09152 Endocrine system
   04924 Renin secretion
    281105 (CTSB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:bta01002]
    281105 (CTSB)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:bta03110]
    281105 (CTSB)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    281105 (CTSB)
   00536 Glycosaminoglycan binding proteins [BR:bta00536]
    281105 (CTSB)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.1  cathepsin B
     281105 (CTSB)
Peptidases and inhibitors [BR:bta01002]
 Cysteine peptidases
  Family C1: papain family
   281105 (CTSB)
Chaperones and folding catalysts [BR:bta03110]
 Intramolecular chaperones
  Papain family
   281105 (CTSB)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   281105 (CTSB)
Glycosaminoglycan binding proteins [BR:bta00536]
 Heparan sulfate / Heparin
  Others
   281105 (CTSB)
SSDB
Motif
Pfam: Peptidase_C1 Propeptide_C1 Peptidase_C1_2
Other DBs
NCBI-GeneID: 281105
NCBI-ProteinID: NP_776456
BGD-bta: BT10007
Ensembl: ENSBTAG00000012442
VGNC: 27813
UniProt: P07688
Structure
Position
8:7566167..7587042
AA seq 335 aa
MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCG
AILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSW
NTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY
NT seq 1008 nt   +upstreamnt  +downstreamnt
atgtggcggctcttggccaccctcagctgcctgctggtgctgaccagtgcccggagcagc
ctgtatttcccgcctctgtccgatgagctggtcaactttgttaacaagcaaaacaccact
tggaaggctggacacaacttctacaacgtggacctgagctatgtgaagaagctgtgtggc
gccatcctgggcgggcccaagctgccccagagagatgcatttgctgcggatgtggttctg
cctgaaagcttcgatgcccgggaacagtggccaaactgcccgaccatcaaagagatcaga
gatcagggatcctgtggctcctgctgggcgttcggggctgtggaagccatttctgaccgg
atctgcatccacagcaatgggcgtgtcaacgtggaggtgtccgctgaggacatgctgacc
tgctgtggtggcgagtgtggggacggctgtaacggcggcttcccctctggagcctggaac
ttctggacaaagaaaggcttagtgtccgggggcctctataactcgcatgtaggttgcaga
ccgtactccatccctccctgtgagcaccatgtgaacggctcccggcccccgtgcaccggt
gagggggacacccccaagtgcagcaagacctgtgagccaggctacagcccgtcctacaaa
gaagacaagcattttggatgcagttcctacagcgtcgccaacaacgagaaggagatcatg
gcagagatctacaaaaatggcccagtcgagggggccttctctgtgtactcggacttcctg
ctatacaagtctggggtgtaccagcacgtctctggagagattatgggaggccacgccatc
cgcatcctaggctggggagtggagaacggcaccccctactggctggtcggcaactcctgg
aacactgattggggtgacaatggcttcttcaaaatcctcagaggacaggaccactgtgga
atcgagtcggaaatcgtggctggaatgccgtgcactcatcagtactag

  All links  
Ontology (6)   
   KEGG BRITE (6)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (10)   
   RefSeq(nuc) (4)   
   GenBank (3)   
   EMBL (3)   
3D Structure (11)   
   PDB (11)   
Protein domain (3)   
   Pfam (3)   
All databases (75)   

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